Product ID:48729, GC-MS KIT-625 BENZIDINE
MSDS Date:02/10/1992
FSC:6810
NIIN:00N032531
Kit Part:Y
MSDS Number: BPBCG

SUPELCO INC

SUPELCO PARK
BELLEFONTE, PA 16823-0048
US

Emergency Phone: 814-359-3441

Info Phone: 814-359-3441

Cage: 54968

SIGMA-ALDRICH INC.

14508 ST. LOUIS, MO 63103 US

Telephone: 314-771-5765/414-273-3850X5996

Cage: 54968

BENZIDINE;((1,1'-BIPHENYL)-4,4'-DIAMINE) (SARA III).

CAS: 92-87-5

RTECS: DC9625000

Fraction By Weight: 0.05%

OSHA PEL SEE 1910.1010

ACGIH TLV: S, A1, 9293

EPA Report Quantity: 1 LB

DOT Report Quantity: 1 LB

(ORAL, RAT)

CAS: 75-09-2

RTECS: PA8050000

Fraction By Weight: 99.95%

OSHA PEL 500 PPM;1000,C

ACGIH TLV: 50 PPM

EPA Report Quantity: 1000 LBS

DOT Report Quantity: 1000 LBS

TO EPINEPHRINE IN LAB ANIMALS/COULD HAVE SIMILAR

RTECS: 9999999ZZ

CONTRAINDICATED EXCEPT FOR LIFE SUSTAINING USES IN

RTECS: 9999999ZZ

NEVER TRY TO MAKE AN UNCONSCIOUS PERSON

RTECS: 9999999ZZ

FLAMES, HOT GLOWING SURFACES OR ELECTRICAL

RTECS: 9999999ZZ

LD50 LC50 Mixture:SEE INGREDIENTS.
Routes of Entry: Inhalation:YES Skin:NO Ingestion:YES
Reports of Carcinogenicity:NTP:YES IARC:YES OSHA:YES
Health Hazards Acute and Chronic:MAY BE FATAL IF INHALED. HARMFUL IF
SWALLOWED. CNTNS MATL KNOWN TO STATE OF CALIFORNIA TO CAUSE CANCER.
LACHRIMATION, IRRITATES SKIN, DERMATITIS. HDCH, DIZZ, NARCOSIS.
LIVER & KIDNEY DMG. SEV CHRONIC INHAL STUDIES REPORTED BY NIOSH
REVEALED THAT TEST ANIMALS EXPOSED TO METHYLENE CHLORIDE CONS AS
HIGH (EFTS OF OVEREXP)
Explanation of Carcinogenicity:METHYLENE CHLORIDE:GROUP 2B (IARC),
ANTICIPATED CARC (NTP). BENZIDINE:OSHA REGULATED, GROUP 1 (IARC),
KNOWN CARC (NTP).
Effects of Overexposure:HLTH HAZ:10,000 PPM SHOWED SLIGHT LIVER/ KIDNEY
CHANGES. METHYLENE CHLORIDE HAS BEEN SHOWN TO INCR RATE OF
SPONTANEOUSLY OCCURING MALIGNANT TUMORS IN ONE STRAIN OF LAB MICE &
BENIGN TUMORS IN LAB RATS . OTHER ANIMAL STUDIES, AS WELL AS SEV
HUMAN EPIDEMIOLOGY STUDIES, HAVE INDICATED A NEGATIVE RESPONSE.
METHYLENE(SUPDAT)
Medical Cond Aggravated by Exposure:NONE SPECIFIED BY MANUFACTURER.

First Aid:EYE:FLUSH W/WATER FOR AT LEAST 15 MINS. SKIN:PROMPTLY WASH
W/MILD SOAP & LRG VOLUMES OF WATER. REMOVE CONTAM CLTHG.
INHAL:IMMED MOVE TO FRESH AIR. GIVE O2 IF BRTHG LABORED. IF BRTHG
STOPS, GIVE ARTF R ESP. CALL MD. NEVER GIVE ADRENALIN FOLLOWING
CH2CL2 EXPOS. INCR SENSITIVITY OF HEART TO ADRENALIN MAY BE CAUSED
BY OVEREXP TO CH2CL2. INGEST:NEVER GIVE ANYTHING BY MOUTH TO UNCON
PERS. (ING 5)

Extinguishing Media:WATER, CO2, DRY CHEMICAL.
Fire Fighting Procedures:WEAR NIOSH/MSHA APPROVED PRESSURE DEMAND SCBA
& FULL PROTECTIVE EQUIPMENT .
Unusual Fire/Explosion Hazard:THE FOLLOWING TOXIC VAPORS ARE FORMED
WHEN THIS MATERIAL IS HEATED TO DECOMPOSITION:HYDROGEN CHLORIDE,
PHOSGENE.

Spill Release Procedures:TAKE UP WITH ABSORBENT MATERIAL. VENTILATE
AREA. METHYLENE CHLORIDE VAPORS ARE HEAVIER THAN AIR & WILL COLLECT
IN LOW AREAS.
Neutralizing Agent:NONE SPECIFIED BY MANUFACTURER.

Handling and Storage Precautions:STORE IN SEALED CONTAINER IN COOL, DRY
LOCATION. POSSIBLE CANCER HAZARD.
Other Precautions:NO SMOKING IN AREA OF USE. DO NOT USE IN THE GENRAL
VICINITY OF ARC WELDING, OPEN FLAMES OR HOT SURFACES. HEAT AND/OR
UV RADIATION MAY CAUSE THE FORMATION OF HCL & PHOSGNE .

Respiratory Protection:WEAR NIOSH/MSHA APPROVED FACE MASK WITH ORGANIC
VAPOR CANISTER.
Ventilation:USE ONLY IN WELL VENTILATED AREA.
Protective Gloves:NEOPRENE GLOVES.
Eye Protection:CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:NOT APPLICABLE.
Work Hygienic Practices:NONE SPECIFIED BY MANUFACTURER.
Supplemental Safety and Health
KEY1;T4. EFTS OF OVEREXP:CHLORIDE IS NOT BELIEVED TO POSE CARC RISK TO
MAN WHEN HANDLED AS REC. CH2CL2 IS METABOLIZED TO CO & CAN STRESS
CVS DUE TO INCR CARBOXYHEMOGLOBIN. IN RATS METHYLENE CHLORIDE H AS
BEEN SHOWN TO PRODUCE A SIGNIF INCR IN SALIVARY GLAND TUMORS.
CHLOROCARBON MATLS HAVE PRODUCED SENSIT OF MYOCARDIUM (

HCC:T4
Boiling Pt:B.P. Text:104F,40C
Melt/Freeze Pt:M.P/F.P Text:-143F,-97C
Vapor Pres:349 @ 20C
Vapor Density:2.93 @ 20C
Spec Gravity:1.320 (H2O=1)
Evaporation Rate & Reference:0.71 (ETHER=1)
Solubility in Water:1.6
Appearance and Odor:CLEAR COLORLESS LIQUID WITH ETHER LIKE ODOR
Percent Volatiles by Volume:100

Stability Indicator/Materials to Avoid:YES
STRONG BASES AND OXIDIZING AGENTS.
Stability Condition to Avoid:LIQ O2 OR OTHER STRONG OXIDANTS MAY FORM
EXPLO MIXTURES W/METHYLENE CHLORIDE. MATL/ITS VAPS WHEN IN CNTCT W/
(ING 6)
Hazardous Decomposition Products:HCL, PHOSGENE.

Waste Disposal Methods:COMPLY WITH ALL APPLICABLE FEDERAL, STATE OR
LOCAL REGULATIONS.

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particular situation.